We use X-ray diffraction data to study proteins and protein-ligand complexes using X-ray Crystallography and SAXS methods as well as novel methodologies applied to glycomics, such as glycan microarrays.
Our main research interests are related to the application and development of solution state nuclear magnetic resonance (NMR) spectroscopy for structural analysis and the study of intermolecular interactions in biological and chemical systems. In the context of the functional analysis of catalytic systems and the understanding of molecular recognition processes we explore: (i) protein-ligand interactions in drug discovery; (ii) solute-solvent interactions; (iii) protein structure and dynamics (iv) new techniques in NMR.