We are pleased to announce that we have confirmed the plenary speakers of the 4th IMDES, namely Prof. Gabriela Guillena Townlwy, from the University of Alicante, Spain; Prof. Sona Raeissi, from the University of Shiraz, Iran; and Prof. Samir Mitragotri, from the Wyss Institute, Harvard University, USA. We believe that these experts will bring very interesting lectures to the public, which is one more reason to attend this Meeting.