Program
Click here to have glance of the schedule in pdf format, or here to have a full version of the program.
| Tuesday, July 16 | |
| 16:00 - 18:15 | Registration |
| 18:30 - 20:00 | Get together / Introductory remarks Welcome drink |
| 20:00 | Dinner |
Wednesday, July 17 |
|
| 09:00 - 09:15 | DMSO Reductase Family Enzymes - Structural and Mechanistic Aspects Chair: A. Magalon (CNRS, France) |
| 09:15 - 09:45 | J. Weiner (University of Alberta, Canada) "Pyranopterin coordination controls catalytic competency in bis-pyranopterin containing enzymes" |
| 09:45 - 10:15 | J. Heider (Philipps University of Marburg, Germany) "Ethylbenzene dehydrogenase and related enzymes: mechanisms and functions" |
| 10:15 - 10:45 | J. Santini (University College London, UK) “Structural and mechanistic studies of the arsenite oxidase” |
| 10:45 - 11:15 | Coffee break |
| 11:15 - 11:45 | B. Guigliarelli (CNRS, France) "Spectroscopic and kinetic studies of substrate interaction with molybdenum cofactor in nitrate reductases" |
| 11:45 - 12:15 | P. Gonzalez (Universidade Nova de Lisboa, Portugal) "Substrate-dependent modulation of the enzymatic catalytic activity: reduction of nitrate, chlorate and perchlorate by respiratory nitrate reductase from Marinobacter hydrocarbonoclasticus 617" |
| 12:15 - 12:45 | P. Arnoux (CNRS - CAE, France) "Structural basis of the molybdenum cofactor sulfuration mechanism of formate dehydrogenases" |
| 12:45 - 13:00 | I. Pereira (ITQB, Universidade Nova de Lisboa, Portugal) "DMSO reductase family proteins in Desulfovibrio vulgaris Hildenborough" |
| 13:00 - 14:30 | Lunch |
| 14:30 - 14:45 | Sulfite Oxidase Family Enzymes - Structural and Mechanistic Aspects Chair: M. Kirk (University of New Mexico, USA) |
| 14:45 - 15:15 | J. Enemark (University of Arizona, USA) "Applications of pulsed EPR spectroscopy to structural studies of sulfite oxidizing enzymes" |
| 15:15 - 15:30 | A. Belaidi (University of Cologne, Germany) "Engineering spin labelled and heme-deficient sulfite oxidase: insights into substrate specificities" |
| 15:30 - 15:45 | B. Stein (University of New Mexico, USA) "Spectroscopic and computational studies of sulfite oxidase family enzymes" |
| 15:45 - 16:00 | K. Schrader (University of Cologne, Germany) "Novel function of plant nitrate reductase N-terminus" |
| 16:00 - 16:15 | P. Ringel (Braunschweig University of Technology, Germany) "Moco-free nitrate reductase from Neurospora crassa" |
| 16:15 - 16:45 | Coffee break |
| 16:45 - 17:00 | Mo/W Enzymes Model Compounds Chair: H. Sugimoto (University of Osaka, Japan) |
| 17:00 - 17:30 | P. Basu (Duquesne University, USA) "New insight to structure-function of oxo-Mo centers from guilty dithiolene ligands" |
| 17:30 - 18:00 | C. Schulzke (Ernst-Moritz-Arndt Universität Greifswald, Germany) "Partly unexpected developments in dithiolene chemistry - Mo and W enzymes' active site models" |
| 18:00 - 18:30 | S. Burgmayer (Bryn Mawr College, USA) "Using model chemistry to investigate the role of the pterin dithiolene ligand in the molybdenum cofactor" |
| 18:30 - 20:00 | Poster session |
| 20:00 | Dinner Palmira Fontes da Costa (Universidade Nova de Lisboa, Portugal) "At the table with Dr. Garcia de Orta" |
Thursday, July 18 |
|
| 09:00 - 09:15 | Xanthine Oxidase Family Enzymes - Structural and Mechanistic Aspects Chair: R. Hille (University of California, Riverside, USA) |
| 09:15 - 09:45 | T. Santos-Silva (Universidade Nova de Lisboa, Portugal) "Bacterial monomeric aldehyde oxidases" |
| 09:45 - 10:15 | P. Bernhardt (University of Queensland, Australia) "Electrochemical communication with molybdoenzymes" |
| 10:15 - 10:30 | C. Coelho (Universidade Nova de Lisboa, Portugal) "Mouse and human aldehyde oxidases” |
| 10:30 - 10:45 | J. Wilcoxen (University of California, Riverside, USA) "Kinetic studies of H2 oxidation by the Mo/Cu-containing carbon monoxide dehydrogenase of Oligotropha carboxydovorans" |
| 10:45 - 11:15 | Coffee break |
| 11:15 - 12:30 | Poster session |
| 12:30 - 12:45 | Young researcher presentation TBA |
| 12:45 - 13:00 | Young researcher presentation TBA |
| 13:00 | Group photo |
| 13:00 - 14:30 | Lunch |
| 14:30 - |
Conference Org. Meeting |
| 14:30 - 18:15 | Free time |
| 18:15 - 18:30 | Medical Aspects and Applications of Mo/W Enzymes Chair: M.J. Romão (Universidade Nova de Lisboa, Portugal) |
| 18:30 - 19:00 | T. Nishino (University of Tokyo, Japan) "What have we learned from the work of development of anti-gout drugs?" |
| 19:00 - 19:30 | G. Schwarz (Cologne University, Germany) "The mitochondrial world of molybdenum: biogenesis, deficiency and novel functions" |
| 19:30 - 20:00 | U. Kappler (University of Queensland, Australia) "Haemophilus influenzae molybdenum enzymes as a mechanism to support bacterial persistence and interactions with epithelial cells" |
| 20:00 | Dinner |
Friday, July 19 |
|
| 09:00 - 09:15 | Cofactor Chemistry and Assembling Chair: R. Mendel (Braunschweig University of Technology, Germany) |
| 09:15 - 09:45 | S. Leimkühler (University of Potsdam, Germany) "Novel aspects on molybdenum cofactor biosynthesis in Escherichia coli" |
| 09:45 - 10:15 | J. Csaszar (University of Cologne, Germany) "Catabolism of the molybdenum cofactor - indentification of the urothione methyltransferase" |
| 10:15 - 10:45 | F. Bittner (Braunschweig University of Technology, Germany) "Final activation of xanthine oxidase family enzymes: new insights into the mechanism of molybdenum cofactor sulfuration" |
| 10:45 - 11:15 | Coffee break |
| 11:15 - 11:30 | Tungsten-containing Enzymes - Structural and Mechanistic Aspects Chair: I. Moura (Universidade Nova de Lisboa, Portugal) |
| 11:30 - 12:00 | G. Rivas (Universidade Nova de Lisboa, Portugal) "Molybdenum and tungsten selectivity in formate dehydrogenases from Desulfovibrio alaskensis G20" |
| 12:00 - 12:30 | M. Boll (University of Freiburg, Germany) "The tungsten-containing benzoyl-CoA reductase complex" |
| 12:30 - 12:45 | R. Liao (Stockholm University, Sweden) "Why is the Mo-substituted W-dependent formaldehyde ferredoxin oxidoreductase not active?" |
| 12:45 - 13:00 | C. Brondino (Universidad Nacional del Litoral, Argentina) "EPR characterization of mononuclear Mo/W enzymes" |
| 13:00 - 14:30 | Lunch |
| 14:30 - 14:45 | Mo/W Enzymes - Theoretical Studies S. Sarkar (Bengal Engineering and Science University, India) |
| 14:45 - 15:15 | M. Kirk (University of New Mexico, USA) "Understanding the pyranopterin cofactor and its role in molybdoenzyme catalysis" |
| 15:15 - 15:45 | N. Cerqueira (Universidade do Porto, Portugal) "The S-shift: an activation mechanism for periplasmic nitrate reductase and formate dehydrogenase" |
| 15:45 - 16:00 | F. Biaso (CNRS, France) DFT calculations and magnetostructural correlations on nitrate reductases Mo(v) species |
| 16:00 - 16:30 | Coffee break |
| 16:30 - 16:45 | Novel Enzymes, Structures and Mechanisms Chair: J.J.G. Moura (Universidade Nova de Lisboa, Portugal) |
| 16:45 - 17:15 | B. Clement (Christian-Albrechts-University of Kiel, Germany) "Novel aspects of the human molybdenum containing enzyme mARC" |
| 17:15 - 17:45 | S. Pauleta (Universidade Nova de Lisboa, Portugal) "A Cu-Mo protein involved in cell division of anaerobic bacteria" |
| 17:45 - 18:00 | B. Maiti (Universidade Nova de Lisboa, Portugal) "Incorporation of molybdenum in iron-site of rubredoxin - a model for molybdoenzymes?" |
| 18:00 - 18:15 | L. Maia (Universidade Nova de Lisboa, Portugal) "Mammalian nitrite-mediated cytoprotection: role of xanthine oxidase and aldehyde oxidase" |
| 18:15 - 18:30 | Nitrogenase - Structural and Mechanistic Aspects Chair: J.J.G. Moura (Universidade Nova de Lisboa, Portugal) |
| 18:30 - 19:00 | L. Seefeldt (Utah State University, USA) "Insights into N2 reduction catalyzed by nitrogenase" |
| 19:00 - 19:30 | O. Einsle (University of Freiburg, Germany) "The structure and properties of FeMo cofactor" |
| 19:30 - 20:00 | M. Ribbe (University of California, Irvine, USA) "Tracing the interstitial carbide of the nitrogenase cofactor" |
| 21:00 | at Seteais Palace Conference dinner / Closing remarks (annoucem. next conference) |
Saturday, July 20 |
|
| - - - | Departure |
Sponsors
CÂMARA MUNICIPAL
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