Inorganic Chemistry, the Periodic Table and Life: copper as a case study

When: April 17, 2019 - 11h00 | reception  // 12h00 | talk
Where: Auditorium of the Library, FCT NOVA

What: Elemental Talks about the Periodic Table | Invited Speakers
Invited speakers address the topic in different perspectives.

   
 

Abstract:
As we celebrate the International Year of the Periodic Table on the occasion of the 150th year anniversary of its discovery, it is appropriate to pay homage to Inorganic Chemistry, the field that encompasses all of the elements. Among all of the varied global impacts of Inorganic Chemistry, it’s role in life processes is particularly important, yet when ‘Biological Inorganic Chemistry’ (or ‘Bioinorganic Chemistry’) is broached as a subject it often garners quizzical looks and the question: What does Inorganic Chemistry have to do with Biology? In this lecture I will attempt to address this question from a personal perspective, both broadly and with specific focus on how the key roles that copper plays in enzymes may be understood through interdisciplinary synthetic chemistry approaches.

Who:

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William B. Tolman

Washington University in St. Louis, USA
Webpage: https://sites.wustl.edu/tolmangrouplaboratory/

He obtained a B.S. degree from Wesleyan University, CT, in 1983, where he performed organometallic chemistry research under the direction of Alan R. Cutler. He did graduate research with K. Peter C. Vollhardt at the University of California, Berkeley, that culminated in a Ph.D. in 1987. He was then introduced to bioinorganic chemistry during a postdoctoral period, 1987-1990, in the laboratory of Stephen J. Lippard at the Massachusetts Institute of Technology. He was appointed as Assistant Professor in the Department of Chemistry at the University of Minnesota in 1990, and rose through the ranks there to Distinguished McKnight University Professor. He is a member of the Center Sustainable Polymers and recently was Chair of the Department of Chemistry (2009-2016). He began his current position at Washington University in St. Louis on January 1, 2018. Among the honors he has received are the Searle Scholars, NSF National Young Investigator, Camille & Henry Dreyfus Foundation Teacher-Scholar, and Alfred P. Sloan Foundation Awards, the Buck-Whitney Medal from the American Chemical Society, a Research Award from the Humboldt Foundation, and the ACS Award for Distinguished Service in the Advancement of Inorganic Chemistry (2017). He is a Fellow of the American Association for the Advancement of Science and the American Chemical Society. He served as Associate Editor (2009-2012) and now as Editor-in-Chief of Inorganic Chemistry (2013-present), and served on the governing boards of the ACS Petroleum Research Fund and the Council for Chemical Research. He also served as Chair of the Gordon Research Conferences on Inorganic Reaction Mechanisms (2005) and Metals in Biology (2011). Current research in his group encompasses synthetic bioinorganic and organometallic/polymer chemistry. In the bioinorganic area, the objective is to gain a fundamental structural, spectroscopic, and mechanistic understanding of metalloprotein active sites of biological and environmental importance via the synthesis, characterization, and examination of the reactivity of model complexes. The current goal of his research in the organometallic/polymer area is to synthesize and characterize a variety of metal complexes for use as catalysts for the polymerization of cyclic esters and for converting biomass feedstocks to useful monomers. In this project, particular emphasis is being placed on developing controlled synthesis of polymers derived from renewable resources.

Event coordinators:
Ana Aguiar-Ricardo
José J. G. Moura

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